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The Revolution of Personalized Medicine

Society November 8th, 2011, Marc-Olivier Bévierre / Partner with Cepton Strategies, Paris

From risk profiling to gene therapy and molecular diagnostics, personalized medicine opens new, exciting fields to medical research. Not only is it good news for the patients: considerable improvements are at stake, both for health systems and pharmaceutical firms now struggling to reinvent themselves. But the road ahead is still full of obstacles.

Nudging Smokers: the New Frontiers of the Fight against Tobacco

Society October 26th, 2011, Alberto Alemanno / Jean Monnet Professor of EU Law & Risk Regulation at HEC Paris

The recently-adopted smoking bans in bars and restaurants epitomize a cultural transformation. By creating an environment where smoking becomes increasingly more difficult, the bans help shift social norms away from the acceptance of smoking in everyday life and promotes public rejection of cigarettes. And this is only the beginning. New public policies such as nudging smokers are now developed, raising legal and moral issues.

Technology-enabled home health care should be thriving. An aging population and the transformation of acute illnesses such as heart failure into chronic diseases mean that the number of patients is growing. In addition, new medical-technology devices could help keep patients at home rather than in costly institutions, such as assisted-living facilities or nursing homes - leading to potentially big savings for the health care systems. Instead, the full potential of the technology-enabled home health care market remains to be tapped.

Unraveling Some of the Brain’s Mysteries

Society October 3rd, 2011, Bernard Esambert / President of the French Foundation for Epilepsy Research and the Federation for Brain Research

Brain malfunctions account for 35% of all diseases in Europe, with an annual cost of 400 billion Euros, well above the costs of cardiovascular disease and cancer. This is not surprising because a complex structure is subject to a huge number of dysfunctions.

In most places in the world, the death rate keeps falling. Even in the West, where we keep doing our best to tempt fate by gaining more weight, the trend continues to be toward longer life. Now some scientists believe the rapid growth of genetic knowledge may make further medical breakthroughs even more likely. How much longer might we live? And how will society cope if we do?

Role Reversal: Science Should Be Leading Technology, Not The Inverse

Science and Technology June 20th, 2011, Françoise Barré-Sinoussi / Head of the unit of regulation of retroviral infections, Institut Pasteur

Looking for balance between science and technology in modern research, we can observe it is the latter in the ascendant. Research is being dictated by the availability of technological resources but in the past, the reverse was true. Projects began by a review of the available data from which a scientific hypothesis was constructed, and finally a search for the best technological tools would begin. Francoise Barre-Sinoussi has suggested that in the rush to embrace technology, researchers may be missing the chance to learn from what worked so well in the past.

Microbes or Men: Who Will Win?

Society April 14th, 2010, Maxime Schwartz / Honorary General Director of Institut Pasteur

Throughout history, changes in human behavior have caused the dissemination of infectious diseases, from smallpox to the flu. But thanks to scientific progress and plain old international cooperation and coordination, we’ve been able to ward off disaster, or at least the worst of it. However, an additional factor will up the stakes for scientists and policymakers worldwide in the fight against emergence or re-emergence: the remarkable adaptive capacities of microbes. The question is, microbes or men, who will win?

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